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br Conflicts of interest br The authors
2019-09-25
Conflicts of interest The authors declare no conflicts of interest. 8. Whittemore AS, Wu-Williams AH, Lee M, Zheng S, Gallagher RP, Jiao DA, et al. Diet, physical activity and colorectal cancer among Chinese in North America and China. J Natl Cancer I. 1990;82:915. 9. O’Keefe SJ, Kidd M,
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br principais sintomas observados em
2019-09-24
principais sintomas observados em pacientes iraquianos. Pacientes e métodos: O estudo avaliou pacientes com câncer colorretal recém-diagnosticado por achados de colonoscopia e confirmados por exame histopatológico de biópsias endoscópicas do cólon. Resultados: O estudo incluiu 63 casos
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br Accepted date br Please cite this article as
2019-09-24
Accepted date: Please cite this article as: Reyna Aguilar Quispe DDS, MSc , Ana Carolina Cunha Rodrigues DDS , Ana Maria Greff Buaes DDS , Ana Lucia Alvares Capelozza DDS, MSc, PhD , Cassia« Maria Fischer Rubira DDS, MSc, PhD , Paulo Sergio« da Silva Santos DDS, MSc, PhD , A CASE-CON
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Genomics xxx xxxx xxx xxx br linear predictor
2019-09-23
Genomics xxx (xxxx) xxx–xxx linear predictor η (eta) which represents the product of the covariate vector x and the parameter vector β. Patients with η > 0 were classi-fied as high-risk patients and those with η Puromycin [31]. 2.6. Comparison with other signatures The commercially avai
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br Results br Patient Characteristics br
2019-09-16
3. Results 3.1. Patient Characteristics Table 1 Characteristics of patients undergoing Recurrence Score (RS) testing. greater N = Percent N = Percent Traditional RS Risk Group TAILORx RS Risk Group Year of Diagnosis Age, years Race Progesterone Receptor Statu
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br Hematoxylin and eosin H E staining and immunohistochemica
2019-09-16
2.16. Hematoxylin and eosin (H&E) staining and immunohistochemical analysis of xenograft tumors The MDA-MB-231 xenograft tumors were removed and fixed in formalin solution (10% neutral buffered formaldehyde) at room tem-perature for 48 h. Slides containing 4 μm section of formalin-fixed and par
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Competing interests br Ethics approval br Funding br Acknowl
2019-09-03
Competing interests Ethics approval Funding Acknowledgments Introduction An increased understanding of the molecular drivers of oncogenesis and resistance in non-small lung cancer (NSCLC) has led to a rapid expansion in the number of targeted therapies available to patients. Accordingly
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As has been reported in other malignancies
2019-09-02
As has been reported in other malignancies, we found that the appearance of the radiographic characteristics of LC on post-surgical follow-up CT was associated with a statistically worse OS and PFS compared to patients that did not develop radiographic evidence of LC on CT. In our cohort of 44 patie
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Adjuvant chemotherapy has proved to be of
2019-08-26
Adjuvant chemotherapy has proved to be of benefit in patients with stage IIA-IIIB NSCLC [25], and though its use in stage IB patients remains controversial, many centers offer adjuvant chemotherapy to patients with tumors ≥4 cm [26]. In our cohort, 20.4% with stage IA disease surprisingly received a
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Even though docetaxel is considered the reference
2019-08-26
Even though docetaxel is considered the reference second-line chemotherapy for advanced NSCLC, in the real-life, its toxicity can't be ignored. With the intent of reducing docetaxel toxicity, in the past decades alternative regimens, consisting of lower doses or different administration schedules, h
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Both IMpower nab paclitaxel carboplatin plus atezolizumab an
2019-08-26
Both IMpower-130 (nab-paclitaxel/carboplatin plus atezolizumab) and IMpower-150 (atezolizumab/carboplatin/paclitaxel plus bevacizumab) enrolled patients with EGFR and ALK positive tumors who had failed at least one line of appropriate TKI therapy. In the subgroup analyses there was a trend for impro
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From the current work it is evident that
2019-08-20
From the current work, it is evident that MM incidence in India exhibits considerable variation across sex, age and geographical regions of the country. A male preponderance was noticed. The MM rates (both crude and age-adjusted) in men exceeded those in women (at zonal as well as national levels),
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b iframe width height src
2019-08-16
r> Materials and Methods Results Discussion The evidence available suggests that Vietnamese women have a low exposure to the known HPV co-factors, with low, constant prevalence of oral contraceptive usage, a low and declining smoking prevalence, and a declining fertility rate [55,56,57,58,71
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Similar to our findings increased prevalence of
2019-08-16
Similar to our findings, increased prevalence of abdominal obesity, as well as increased triglyceride and HDL levels, were reported in breast cancer survivors [12]. Studies also reported increased prevalence of high HDL levels in breast cancer survivors [7,12], however, the HDL difference was not st
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The best hope lies in combination
2019-08-16
The best hope lies in combination therapy, wherein potent inhibitors coupled with effective chemotherapy can be used to target specific tumor types for a favorable outcome. In the case of EGFR, which is overexpressed in 90% of pancreatic cancer patients, tyrosine kinase inhibitors (TKI) like eroltin